You are here: Home » Past Issues » Volume 4, 2009 - Number 1 » EFFECTS OF SUBACUTE TREATMENT WITH LEAD ACETATE ON THE MINERAL CONSTITUENTS FROM FEMUR AND TIBIA
Stela-Gabriela JELEA & Marian JELEA
North University of Baia Mare, Science Faculty, 76 Victoriei Street, 430122 Baia Mare, Romania, email@example.com
EFFECTS OF SUBACUTE TREATMENT WITH LEAD ACETATE ON THE MINERAL CONSTITUENTS FROM FEMUR AND TIBIA
Lead acetate was administered in Wistar rats, by intra-gastric tube, for 7 days, in doses of 10 mg/100g body weight, daily. The effects were monitored after 7 days of treatment and after 7 days post therapeutic pause. A group of animals, which were administered water by the same route, served as stress controls. The animals were sacrificed and were taken femur and tibia. There were intensive positive modifications in the weight and sizes of the investigated bones, tibia and femur, after the 7 days of treatment, which persisted after the end of the therapy. Persistent changes were observed in the mineral composition of the bones, even after the treatment ended.
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